
参考文献
[1]陆彬.药物新剂型和新技术.北京:人民卫生出版社,1998.
[2]Couteau C,peraz C N,Connan A E,et al.Stripping method to quantify absorption of two sunscreens in human.Int J Pharm,2001,222:153-157.
[3]Howes D,Guy R,Hadrgft J,et al.Methods for Assessing Percutaneous Absorption.ATLA:81-106.
[4]Mose K,Driwet K,Naik A,et al.Passive skin penetration enhancement and its quantification in vitro.Euro J Pharm Biopharm,2001,52:103-112.
[5]冯华,郑家润.经皮吸收实验技术.国外医学皮肤性病学分册,2003,29:243-246.
[6]Touitou E,Medin V M,Horwitz E.Methods for quantitative determination of drug localized in skin.J Control Release,1998,56:7-21.
[7]Seki T,Hosoya O,Yanmazaki T,et al.A rabbit ear flap perfusion expexperiment to evaluate the percutaneous absorption of drugs.Int J pharm,2004,276:29-40.
[8]Cross S,Wu Z,Roberts,M S.Effect of perfusion fiow rate on the tissue uptake of solutes after dermal application using the rate isolated perfused hinglimb preparation.J Pharm Pharmacol,1994,46:844-850.
[9]Cantor A S.Drug and excipient diffusion and solubility in acrylate adhesives measured by infrared-attenuated total reflectance(IR-ATR)spectroscopy.J Controlled Release,1999,61:219-231.
[10]姜丽丽,徐敏,金大源等.α-细辛醚贴剂的家兔相对生物利用度研究.中国药学杂志,2002,19:390-391.
[11]张学军,刘维达,何春涤.现代皮肤病学基础.北京:人民卫生出版社,2001.
[12]Benfeldt E,Groth L.Feasibility of measuring lipophilic or protein-bound drugs in the dermis by in vivo microdialysis after topical or systemic drug administration.Acta Derm Venereol,1998,78:274-278.
[13]Williams A C.Structure and Fuction of Human Skin.In:Williams A C.Transdermal and Topical Drug Delivery. JA Majors Co,2003:1-25.
[14]Anigbogu A N C,Williams A C,Barry B W.Permeation characteristics of 8-methoxypsoralen through human skin:relevance to clinical treatment.J P harm Pharmacol,1996,48:357-366.
[15]郑俊民.经皮给药新剂型.北京:人民卫生出版社,1997:36-39.
[16]Cross S E,Roberts M S.Subcutaneous absorption kinetics of interferon and other solutes.J Pharm Pharmacol, 1993,45:606-609.
[17]King M J,Michel D,Foldvari M.Evidence for lymphatic transport of insulin by topically applied biphasic vesicles.J Pharm Parmacol,2003,55:1339-1344.
[18]Flynn G L.Cutaneous and Transdermal Delivery-Processes and Systems of Delivery.In:Banker G S,Rhodes C T, eds.Modern Pharmaceutics.New York:Marcel Dekker,2002:187-223.
[19]Lampe M A,Burligame A L,Whitney J,et al.Human stratum corneum lipids:characterisation and regional variations.J Lipid Res,1983,24:120-130.
[20]Finnin B C,Morgan T M.Transdermal penetration enhancers:application,limitations,and potential.J Pharm Sci, 1999,88:955-958.
[21]Modamio P,Lastra C F,Marino E L.A comparative in vitro study of percutaneous penetration of β-blockers in human skin.Int J Pharm,2000,194:249-259.
[22]Rathbone M J,Hadgraft J,Roberts M S.Modified-Release Drug Delivery Technology.New York:Marcel Dekker, 2003:488.
[23]Qi X H,Ackermann C,Sun D,et al.Physicochemical characterization and percutaneous delivery of 2,3,5,6-tetra-methylpyrazine.Int J Pharm,2003,253:177-183.
[24]刘建平,李运曼,张灵霞等.止咳平喘膜剂的研制与穴位作用机理初步探讨.中国药科大学学报,2000,31:426-428.
[25]Berardesca E,Maibach H I.Racial differences in pharmacodynamic response to nicotinates in vivo in human skin:black and white.Acta Derm Venereol,1990,70:63-66.
[26]Wilhelm K,Surber C,Maibach H I.Effect of sodium laurylsulfate-induced skin irritation on in vivo percutaneous absorption of four drugs.J Invest Dermatol,1991,97:927-932.
[27]Wertz P W,Miethke M C,Long S A,et al.The composition of the ceramides from human stratum corneum and from comedones.J Invest Dermatol,1985,84:410-412.
[28]Roberts M S,Walters K A.The relationship between structure and barrier function of skin.In:Roberts M S, Walters K A,eds.Dermal Absorption and Toxicity Assessment.New York:Marcel Dwkker,1998:chapter 1.
[29]Fenske N A,Lober C W.Structural and functional changes of normal aging skin.J Am Acad Dermatol,1986,48:571-585.
[30]Berardesca E,Rigal J L,et al.In vivo biophysical characterization of skin physiological differences in races.Dermatologica, 1991,182:89-93.
[31]Lotte C,Wester R C,Rougier A,et al.Racial differences in the vivo percutaneous absorption of some organic compounds:a comparison between black,Caucasian and Asian subjects.Arch Dermatol Res,1993,284:456-459.
[32]Goldin B,Touitou E.Ethosomes:New Prospects in Transdermal Delivery.Crit Rev Ther Drug,2003,20:63-102.
[33]Adrian C W,Barry W B.Terpenes and the lipid-protein-partitioning theory of skin penetration enhancement.Pharm Res,1991,8:17-24.
[34]Abraham M H,Chadha H S,Martins F,et al.Hydrogen bonding part 46:A review of the correlation and prediction of transport properties by an LFER method:physicochemical properties,brain penetration and skin permeability.Pestic Sci,1999,55:78-88.
[35]Patel H,Berge W,Cronin M TD.Quantitative structure-activity relationship(QSARs)for the prediction and skin permeation of exogenous chemicals.Chemosphere,2002,48:603-613.
[36]Magnusson B M,Anissimov Y G,Cross S E,et al.Molecular size as the main determinant of solute maximum flux across skin.J Invest Dermatol,2004,122:993-999.
[37]李娟,纪涛,王雪松.美洛昔康凝胶剂的制备及其经皮吸收研究.中国新药杂志,2002,11:937-939.
[38]刘未艾,叶德宝.穴位贴敷疗法透皮给药的研究进展.中医药通报,2004,3:59-62.
[39]魏莉,蔡贞贞,徐莲英.当归及其复方透皮吸收特性的研究.2000,25:32-34.